Cannabis administration is associated with decreased migraine headache frequency, according to data published online ahead of print in the journal Pharmacotherapy.
Investigators at the University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences retrospectively assessed cannabis’ effects on monthly migraine headache frequency in a group of 121 adults. Study participants had a primary diagnosis of migraine headache, had been recommended cannabis by a physician for migraine treatment and had participated in at least one follow up medical visit.
Authors reported that 85 percent of subjects reported a decrease in migraine frequency, and 12 percent indicated that the use of cannabis prior to migraine onset would abort headaches.
“Migraine headache frequency decreased from 10.4 to 4.6 headache per month with the use of medical marijuana,” researchers concluded. “Further research should be performed to determine if there is a preferred delivery method, dose, and strain of medical marijuana for migraine headache therapy as well as potential long-term effects of medical marijuana.”
Although case reports have previously documented the effect of cannabinoids for migraine relief, no prospective trials have yet to evaluate cannabis use in migraine patients.
Nonetheless, scientists for some time have theorized that cannabinoids may play a role in migraine regulation.
Writing in 2007, in the European Journal of Critical Pharmacology, Italian researchers reported that patients with chronic migraines possessed significantly lower levels of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol (2-AG) in their platelets compared to age-matched controls.
“These data support the potential involvement of a dysfunctioning of the endocannabinoid and serotonergic systems in the pathology of chronic migraine and medication-overuse headaches,” authors concluded.
The abstract of the study, “Effects of medical marijuana on migraine headache frequency in an adult population,” appears online HERE.
(Photo Courtesy of Neurology.org)
Survey Indicates Teen Marijuana Use in Colorado is Lower Than National Average
Family of Man Killed by Bulldozer After Growing Pot Sues Police
Ban on Smokable Medical Marijuana Officially Repealed in Florida
High Folks: Yareem Barnes-Ivey Balances the Two Worlds of Cannabis
Knowledgeable Dabbing: A Guide To Our Favorite Quartz Bangers
First Clinical Trial Of Cannabis For PTSD in Veterans Is Now Complete
Missouri Police Raid Hospital Room of Stage 4 Cancer Patient Using Cannabis
Oklahoma House Passes Medical Cannabis Protection Bill
News4 days ago
Indiana State Trooper Seizes $3.5 Million Worth of Cannabis, Vapes
News4 days ago
Colorado Researchers Seeking Volunteers to Get High and Drive
News5 days ago
Study Finds Medical Marijuana Alleviates Seniors’ Pain, Reduces Opioid Use
News6 days ago
Survey Shows 25% of Cannabis Users in Legal States Consume at Work
Legalization5 days ago
Breaking: Connecticut Lawmakers Unveil Plan to Legalize Marijuana
Culture4 days ago
The New “Miss Marijuana” Pageant Comes With Outdated Guidelines and Transphobia
News7 days ago
$2.5 Million Worth of Marijuana Seized at Philadelphia Port
Grow5 days ago
An Interview With Dinafem Seeds: Europe’s King Of Feminized Seeds